Survey of related factors of maternal venous thromboembolism in nine hospitals of China
10.3760/cma.j.cn112141-20200414-00326
- VernacularTitle:中国九家医院孕产妇静脉血栓栓塞症的发病现状及危险因素调查
- Author:
Zilian WANG
1
;
Huizhen GENG
;
Xianlan ZHAO
;
Qiying ZHU
;
Jianhua LIN
;
Li ZOU
;
Yang MI
;
Yali HU
;
Shangrong FAN
;
Xu CHEN
;
Zhe LIU
;
Huixia YANG
Author Information
1. 中山大学附属第一医院产科，广州 510080
- From:
Chinese Journal of Obstetrics and Gynecology
2020;55(10):667-672
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate and analyze disease status and risk factors of venous thromboembolism (VTE) during pregnancy and puerperium in our country.Methods:Clinical datas were collected from 575 patients diagnosed with VTE during pregnancy and puerperium and hospitalized in nine medical institutions in our country from January 1, 2015 to November 30, 2019, and retrospectively analyzed it′s disease status and risk factors.Results:(1) The proportion of VTE in pregnancy and puerperium was 50.6% (291/575) and 49.4% (284/575), respectively. Four patients died, the mortality rate was 0.7% (4/575). The cause of death was pulmonary embolism. (2) The location of VTE during pregnancy and puerperium was mainly in the lower limb vascular (76.2%, 438/575), followed by pulmonary vessels (7.1%, 41/575). (3) In the risk factors of VTE, cesarean section accounted for 32.3% (186/575), maternal advance age accounted for 27.7% (159/575), braking or hospitalization during pregnancy accounted for 13.6% (78/575), other risk factors accounted for more than 5% were previous VTE, obesity, preterm birth, assistant reproductive technology conception and so on, pre-eclampsia and multiple pregnancy accounted for 4.9% (28/575) respectively. In addition, some patients with VTE did not have any of the above risk factors, and the incidence rate was as high as 23.1% (133/575).Conclusions:The occurrence of VTE during pregnancy and puerperium is related to multiple risk factors, and could lead to matemal death, It is very necessary to screen VTE risk factors for all pregnant women, to make corresponding prevention and control measures.
