Effects of adenosine stress on left ventricular myocardial strain mechanics in healthy rabbits
10.3760/cma.j.cn131148-20200525-00427
- VernacularTitle:腺苷负荷对健康家兔左室心肌应变力学的影响
- Author:
Lingdan GUO
1
;
Youbin DENG
;
Jiayu WANG
;
Weihong ZHU
;
Xiaomei WU
;
Peng DENG
;
Li LI
Author Information
1. 华中科技大学同济医学院附属武汉中心医院超声影像科 430014
- From:
Chinese Journal of Ultrasonography
2020;29(10):897-900
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the changes of myocardial strain mechanics in healthy rabbits in the physiological condition by using speckle tracking echocardiography (STE) combined with adenosine stress.Methods:Twenty healthy rabbits underwent STE both at rest and during adenosine stress. The dynamic original images of 3 consecutive cardiac cycles of the standard views from the left ventricular (LV) short axis and apical long axis were acquired and analyzed by the Echo PAC workstation. The procedure was performed to obtain LV global longitudinal peak strain, global circumferential peak strain, and global radial peak strain both at rest and during adenosine stress.Results:There were no significant differences in heart rate and LV structural and functional parameters between baseline and adenosine stress ( P>0.05). After adenosine stress, LV global longitudinal peak strain and global circumferential peak strain increased significantly when compared with those at rest ( P<0.001), while LV global radial peak strain did not change significantly( P>0.05). Conclusions:Adenosine stress echocardiography combined with STE can be used to evaluate the characteristics of myocardial strain mechanics in rabbits in the physiological condition. This research provides reference value for the application of adenosine stress echocardiography in rabbit models with cardiovascular disease in future.
