The application value of the tissue dispersion quantitative analysis technique in differentiating thyroid nodules
10.3760/cma.j.cn131148-20200508-00380
- VernacularTitle:组织弥散定量技术在甲状腺结节鉴别诊断中的价值探讨
- Author:
Chuanju ZHANG
1
;
Bowen ZHAO
;
Jianghong LYU
;
Haishan XU
;
Jinduo SHOU
;
Lilong XU
;
Liming YANG
;
Jiang ZHU
Author Information
1. 浙江大学医学院附属邵逸夫医院超声科，杭州 310016
- From:
Chinese Journal of Ultrasonography
2020;29(10):870-874
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the application value of the ultrasonic elastic tissue dispersion quantitative analysis technique in differentiating thyroid nodules.Methods:A total of 164 nodules in 143 patients with thyroid nodules were examined by elastography ultrasound at Sir Run Run Shaw Hospital of Zhejiang University School of Medicine from January to November 2014. Eleven parameters were obtained by the tissue dispersion quantitative analysis software. These parameters were compared between benign and malignant groups by Mann-Whitney U test. The correlations between all the parameters and the pathologic results of thyroid nodules were analyzed by Spearman analysis. The receiver operating characteristic(ROC) curve of the parameter with the highest correlation coefficient was constructed. The cut-off value was calculated. Results:All parameters except correlation (CORR) had statistically significant differences between the groups of benign and malignant thyroid nodules(all P<0.01). Moreover, except CORR, the other parameters were correlated with the pathologic results of thyroid nodules(all P<0.05), with the highest coefficient in area ration of low-strain region (%AREA)( r s=0.818). ROC curves were constructed to estimate the clinic values of %AREA in diagnosis of thyroid cancer, the area under ROC curve was 0.991 for %AREA, the cut-off point was 74.83%, the sensitivity and specifity was 98.1% and 89.8%, respectively. Conclusions:The tissue dispersion quantitative analysis technique has high value in the differential diagnosis of benign and malignant thyroid nodules.
