The post left atrium space index in normal fetus and its diagnostic value for fetal isolated total anomalous pulmonary venous connection
10.3760/cma.j.cn131148-20200411-00288
- VernacularTitle:正常胎儿左心房后间隙指数及其对胎儿单纯完全性肺静脉异位引流的诊断价值
- Author:
Jiancheng HAN
1
;
Tianjing LI
;
Jingyi WANG
;
Xiaowei LIU
;
Xiaoyan GU
;
Ye ZHANG
;
Lin SUN
;
Ying ZHAO
;
Zhuo CHEN
;
Yong GUO
;
Chao XUE
;
Ye LI
;
Yihua HE
Author Information
1. 首都医科附属北京安贞医院超声科 100029
- From:
Chinese Journal of Ultrasonography
2020;29(9):743-748
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the value of post left atrium space index (PLASI) in the diagnosis of fetal isolated total anomalous pulmonary venous connection (TAPVC).Methods:Twenty-six cases of fetal isolated TAPVC were retrospectively analyzed as the TAPVC group and 243 normal fetuses were selected as the control group from October 2012 to April 2019 in the Consultation Center of Maternal-Fetus Medicine in Fetal Heart Disease in Beijing An Zhen Hospital. The width of the PLAS and the diameter of the descending aorta were measured in the four chamber view, and then the PLAS index (PLASI) (the width of the PLAS/the diameter of the descending aorta) was calculated. The relationships between the width of PLAS, the diameter of descending aorta and the PLASI and gestational age were analyzed. The difference of the PLASI between isolated TAPVC group and control group was analyzed, and ROC curve was used to analyze the sensitivity and specificity in identifying the isolated TAPVC fetuses and normal fetuses.Results:In the 243 normal fetuses in control group, both the width of the PLAS and the diameter of the descending aorta increased with gestational age ( r s=0.362, 0.648, P<0.05). There was no statistically significant correlation between the PLASI and gestational age ( r s=-0.065, P>0.05). The PLAS and the PLASI in isolated TAPVC group were all significantly higher than those in control group ( t=26.31, 34.90, P<0.01). Based on the ROC curve analysis, when the cutoff value was set to 3.6 mm, the sensitivity and specificity of PLAS in identifying isolated TAPVC and normal fetuses were 97.5% and 100%, respectively. When the cutoff value was set to 1.1, the sensitivity and specificity of PLASI in identifying isolated TAPVC and normal fetuses were 100% and 100%, respectively. Conclusions:The PLASI is a sensitive parameter in identifying the isolated TAPVC, which is helpful for the rapid screening of the isolated TAPVC.
