The value of contrast-enhanced ultrasound in the differentiation of renal oncocytoma and chromophobe renal cell carcinoma
10.3760/cma.j.cn131148-20200309-00158
- VernacularTitle:超声造影鉴别肾嗜酸细胞腺瘤及嫌色细胞癌的应用价值探讨
- Author:
Cuixian LI
1
;
Beijian HUANG
;
Qing LU
;
Jingjing WANG
;
Peilei WANG
;
Cong LI
;
Wenping WANG
Author Information
1. 复旦大学附属中山医院超声科，上海 200032；上海市影像医学研究所 200032
- From:
Chinese Journal of Ultrasonography
2020;29(8):684-689
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the value of contrast-enhanced ultrasound(CEUS) in distinguishing of renal oncocytoma(RO) and chromophobe renal cell carcinoma(chRCC).Methods:The ultrasonic image features of 49 ROs and 72 chRCCs between October 2007 and January 2020 were retrospectively analyzed, all lesions underwent ultrasonic examination (including 19 ROs and 70 chRCCs with CEUS imaging) and were pathologically approved in our institution. The statistically significant parameters from univariate analyses were then entered for further multivariable Logistic regression. The value of each ultrasonic imaging feature in differentiating RO and chRCC was evaluated.Results:According to the univariate analyses, all imaging features on conventional ultrasound were not statistically different between RO and chRCC (all P>0.05), while the characteristics of tumor wash-in/out pattern, enhancement degree and homogeneity at peak time and pseudocapsule around tumor were significantly different (all P<0.05). After multivariable analyses, tumor wash-in and wash-out pattern were excluded for tumor differentiation ( P>0.05), and the parameters of enhancement degree or homogeneity at peak time and pseudocapsule around tumor were still significantly different between tumor types (all P<0.05, odd ratio was 8.683, 6.667 and 18.774 respectively). The overall sensitivity, specificity and accuracy of these three parameters in diagnosing RO was 68.4%, 91.4% and 86.5%, respectively. Conclusions:CEUS can provide some useful information for the differentiation of RO and chRCC.
