Ultrasound-guided post-mortem tissue sampling in the autopsy of COVID-19 cases: a pilot study
10.3760/cma.j.cn131148-20200422-00330
- VernacularTitle:超声引导病理穿刺取材在新型冠状病毒肺炎尸检中的初步应用
- Author:
Cheng YU
1
;
Yi ZHENG
;
Sihua WANG
;
Xiang LI
;
Junjie ZHOU
;
Danqing ZHANG
;
Jing WANG
;
Qing LYU
;
Li ZHANG
;
Yali YANG
;
Mingxing XIE
Author Information
1. 华中科技大学同济医学院附属协和医院超声影像科 湖北省分子影像重点实验室，武汉 430022
- From:
Chinese Journal of Ultrasonography
2020;29(7):553-558
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the application of post-mortem tissue sampling under ultrasonography guidance in the autopsy of COVID-19 cases.Methods:Ultrasound-guided post-mortem tissue sampling of heart, lungs, liver, kidneys, and spleen were performed in 24 confirmed COVID-19 cases in Union Hospital, Tongji Medical College, Huazhong University of Science and Technology from Feb 20 to Mar 28, 2020. Seventeen males and seven females aged 39-91(66.6±10.6) years old were enrolled. The total time required for each post-mortem sampling was recorded, and the size of the samples collected from each organ was measured. The success rate of ultrasound-guided post-mortem tissue sampling for each organ was calculated.Results:Ultrasound images could clearly show the needle path and enabled accurate placement of the needle within the target organs, including heart, lung, liver, kidney, and spleen. The total time required for sampling was about 32-54 (39.8±5.7)min. The lengths of heart, lung, liver, kidney, and spleen tissues collected by ultrasound-guided sampling were 10(8, 14)mm, 13(12, 15)mm, 14(13, 15)mm, 13(11, 15)mm, 14(13, 15)mm, respectively. The success rates of heart, lung, liver, kidney, and spleen tissue sampling under ultrasound guidance were 87.5% (21/24), 91.7%(44/48), 100%(24/24), 89.6%(43/48) and 83.3%(20/24), respectively.Conclusions:Post-mortem sampling under ultrasonography guidance may be a rapid and reliable method for collecting of heart, lung, liver, kidney, and spleen tissues in the autopsy of COVID-19 cases.
