The predictive value of cerebroplacental ratio in stageⅡof twin-twin transfusion syndrome
10.3760/cma.j.cn131148-20191212-00769
- VernacularTitle:脑－胎盘率在预测双胎输血综合征Ⅱ期中的价值
- Author:
Hongli LIU
1
;
Xing WANG
;
Shuai HUANG
;
Lan ZHANG
;
Junnan LI
;
Hongbo QI
Author Information
1. 重庆医科大学附属第一医院产科 重庆市胎儿医学中心 400016
- From:
Chinese Journal of Ultrasonography
2020;29(6):478-482
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the cerebroplacental blood flow distribution characteristics in monochorionic-diamniotic(MCDA) twin pregnancies with stageⅠ-Ⅱof twin-twin transfusion syndrome (TTTS), and investigate the predictive value of cerebroplacental ratio (CPR) in the stageⅡ of TTTS.Methods:The cerebroplacental blood flow distribution were analyzed retrospectively in 68 cases from June 2017 to June 2019 in the First Affiliated Hospital of Chongqing Medical University (34 cases for each stage) with TTTS, including the umbilical artery pulsatility index (UA-PI), middle cerebral artery peak systolic velocity (MCA-PSV), middle cerebral artery pulsatility index (MCA-PI), CPR, and their discordances(UA-PI disc, MCA-PSV disc, MCA-PI disc and CPR disc). Results:The differences of UA-PI, MCA-PI, and CPR between donors and recipients in TTTS Ⅱ were statistically significant (all P<0.05), the differences of UA-PI disc, MCA-PI disc and CPR disc between TTTS Ⅰ and TTTS Ⅱ were statistically significant (all P<0.05). Multivariate Logistic regression analyses showed that only CPR disc was independently associated with the stage Ⅱ of TTTS( P<0.05), and it had moderate predictive accuracy for the stage Ⅱ of TTTS with an area under the curve of 0.766, a sensitivity of 64.71% and a specificity of 82.35%( P<0.001). Conclusions:More cerebroplacental blood flow discordances are observed and CPR disc is closely related to stageⅡof TTTS.
