Research advances in effect of microglia on pathophysiology following traumatic brain injury
10.3760/cma.j.issn.1001-8050.2020.08.013
- VernacularTitle:小胶质细胞对创伤性脑损伤病理生理影响的研究进展
- Author:
Yuxiao MA
1
;
Chun YANG
;
Junfeng FENG
Author Information
1. 上海交通大学医学院附属仁济医院神经外科，上海市颅脑创伤研究所 200127
- From:
Chinese Journal of Trauma
2020;36(8):743-748
- CountryChina
- Language:Chinese
-
Abstract:
Microglia are the immune cells in central neural system. Microglia play an important role in central neural system such as surrounding environment monitoring, apoptosis induction and mature synapse formation. Besides, as a pathological process, traumatic brain injury (TBI) can cause the structure and function damage of central nervous system. While the activated microglia can change the TBI-induced pathological process and play an important role during the course of injury. Therefore, the authors review the important physiological function of microglia and its pathological role so as to provide references for clinical treatment.
