Epidemic and clinical characteristics of 1 976 children with hand-feet-mouth disease in Chengdu, 2018 to 2019
10.3760/cma.j.cn311365-20191115-00374
- VernacularTitle:2018年至2019年成都地区1 976例手足口病患儿的流行病学和临床特征
- Author:
Wenxiao PANG
1
;
Zhaoyong ZHANG
;
Ying LAN
;
Yilan ZENG
Author Information
1. 成都市公共卫生临床医疗中心传染病研究室 610066
- From:
Chinese Journal of Infectious Diseases
2020;38(9):575-577
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the epidemiological and clinical characteristics of hand-feet-mouth disease (HFMD).Methods:The clinical and pathogenic data of 1 976 cases with HFMD hospitalized in Public Health Clinical Center of Chengdu from August 2018 to September 2019 were retrospective analyzed.Results:Among the 1 976 cases of HFMD, 1 094 cases (55.36%) were one to two years old, and 803 cases (40.64%) lived in the main urban area. The majority were scattered patients (1 344 cases, 68.02%). There were 1 348(72.7%) of 1 854 cases mainly infected by Coxsackie virus 6 (CV-A6). The main distribution of rashes in children infected by CV-A6 were palm/soles, trunks, limbs, oral ulcer and perioral areal, lips and hip. The types of rash were maculopapule, vesicle, and bulla. Fever (1 543 cases, 78.09%) was the main concomitant symptom. Acute tonsillitis (811 cases, 41.04%), myocardial injury (767 cases, 38.82%), and herpetic angina (658 cases, 33.30%) were the most common complications. The incidence of onychomadesis were nine (7.03%) among the 128 patients during follow-up.Conclusions:CV-A6 is the main pathogen of the HFMD prevalence. Children less than two years old are susceptible and the main symptoms of HFMD are rash and fever.
