Melanosis Ilei Associated with Chronic Ingestion of Oral Iron.
- Author:
Jae Myung CHA
1
;
Joung Il LEE
;
Kwang Ro JOO
;
Sung Won JUNG
;
Hyun Phil SHIN
Author Information
1. Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea. dramc@hanmail.net
- Publication Type:Case Report
- Keywords:
Hemosiderin;
Melanosis;
Ileum
- MeSH:
Adult;
Colon;
Colonoscopy;
Eating;
Female;
Ferrous Compounds;
Gastrointestinal Tract;
Hemosiderin;
Hemosiderosis;
Humans;
Ileum;
Iron;
Kidney Failure, Chronic;
Melanosis;
Mucous Membrane;
Pigmentation
- From:Gut and Liver
2009;3(4):315-317
- CountryRepublic of Korea
- Language:English
-
Abstract:
Melanosis can affect various parts of the gastrointestinal tract. Melanosis of the colon is not uncommon, while melanosis of the ileum is extremely rare. We report a case of melanosis ilei associated with chronic ingestion of oral iron (256 mg of ferrous sulfate once or twice daily for approximately 5 years) in a 32-year-old woman with end-stage renal disease. The findings of a colonoscopy, which was performed as a part of her medical checkup, were normal up to the cecum; however, numerous brownish-black punctuate pigmentations of the ileal mucosa were observed. Microscopic examination revealed hemosiderosis in the lamina propria of the ileal mucosa, particularly at the tips of villi. The diagnosis of melanosis (hemosiderosis) ilei was made based on the endoscopic and histological findings.