The relationship between lung miacrobiome and lung cancer
10.3760/cma.j.cn431274-20191016-01180
- VernacularTitle:人肺微生物组与肺癌的关系
- Author:
Weichun LI
1
;
Lingling SU
;
Aiping ZHANG
;
Rongrong ZHANG
;
Yun CAO
;
Liang YANG
Author Information
1. 南京中医药大学附属姜堰医院，泰州市姜堰中医院呼吸科 225500
- From:
Journal of Chinese Physician
2020;22(11):1757-1760,f3
- CountryChina
- Language:Chinese
-
Abstract:
The mucosal surfaces of the human body are typically colonized by polymicrobial communities, they exist in the gastrointestinal tract, skin, oral cavity, and genitourinary tract, as well as in anatomical sites previously considered sterile, including the lung. These communities interact with the mucosal immune system to maintain homeostasis in health, emphasizing the important role of " second genome" , which is very important to human health. The human lower respiratory tract also harbor many microbes, the imbalance of microbiome composition maybe critically related with many lung disease. Up to date, researches on microbiome of lung caner is still on the first step. Our review mainly describes the characteristic composition of lung microbiome, and the relationship with diseases, especially with lung cancer. We attempts to provide the basis information for further researches about the relationship between human lung microbiome and lung cancer.
