Progress in diagnosis and treatment of fungal infection in premature infants
10.3760/cma.j.cn431274-20190610-00681
- VernacularTitle:早产儿真菌感染的诊疗进展
- Author:
Huimin XU
1
;
Yunqin WU
;
Xirong GAO
Author Information
1. 南华大学儿科学院,长沙 410007
- From:
Journal of Chinese Physician
2020;22(6):945-948
- CountryChina
- Language:Chinese
-
Abstract:
Due to low autoimmune function, imperfect development of various organs, coupled with a variety of invasive operations and other factors, premature infants are high-risk groups of invasive fungal infection.Invasive candida infection in premature infants accounts for more than 80% of invasive fungal infection. The main infection rate of invasive candida albicans was candida albicans. However, in recent years, the infection rate of non-candida albicans such as candida albicans, tropical candida, smooth candida and other non-candida albicans showed a gradual upward trend.In addition to blood culture, the latest diagnostic methods such as plasma (1-3)-β-D-glucan test and candida polymerase chain reaction are helpful for the diagnosis of invasive fungal infection. At the same time, attention should also be paid to prophylactic antifungal therapy and empirical antifungal therapy in premature infants.