Effect of CYP2C19 genotyping to clopidogrel high reactivity
10.3760/cma.j.cn431274-20200226-00197
- VernacularTitle:CYP2C19基因分型对氯吡格雷高反应性的影响
- Author:
Dongcai FENG
1
;
Yechen HAN
;
Hongzhi XIE
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院心内科 100730
- From:
Journal of Chinese Physician
2020;22(5):794-797
- CountryChina
- Language:Chinese
-
Abstract:
Percutaneous coronary intervention is an important method for the treatment of coronary heart disease. Postoperative dual antiplatelet therapy is an important prerequisite to ensure the safety of surgery. Antiplatelet therapy with clopidogrel still has a high risk of thrombosis, which may be related to CYP2C19 genotyping. Therefore, a brief review of the impact of CYP2C19 genotyping on clopidogrel hyperresponsiveness is made.