Bone Health and Clinical Results after Hip Fracture Surgery in Patients with Subclinical Hypothyroidism.
10.11005/jbm.2014.21.3.213
- Author:
Ki Choul KIM
1
;
Young Kyun LEE
;
You Jin LEE
;
Yong Chan HA
;
Kyung Hoi KOO
Author Information
1. Department of Orthopedic Surgery, Dankook University School of Medicine, Cheonan, Korea.
- Publication Type:Original Article
- Keywords:
Bone density;
Fractures bone;
Hip fractures;
Hypothyroidism
- MeSH:
Bone Density;
Femur;
Hip Fractures;
Hip*;
Humans;
Hypothyroidism*;
Intensive Care Units;
Length of Stay;
Mortality;
Thyroid Gland;
Vitamin D
- From:Journal of Bone Metabolism
2014;21(3):213-216
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Subclinical thyroid dysfunction might influence a bone health. We evaluated whether subclinical hypothyroidism adversely affects bone health including bone mineral density (BMD), level of vitamin D, and bone turnover status in patients with hip fracture. METHODS: We evaluated 471 patients aged 50 years or older, who underwent hip fracture surgeries. BMD, level of vitamin D, bone turnover status, and one-year mortality were compared between subclinical hypothyroidism group and control group. RESULTS: BMD of femur and the level of 25-hydroxy-vitamin D (25-[OH]D) were similar in the two groups. There were no significant differences in bone turnover markers according to thyroid function. No significant differences were observed between the groups in utilization of intensive care unit (ICU), length of hospital stay, mobility, and one-year mortality. CONCLUSIONS: Subclinical hypothyroidism was not associated with reduced bone health, including BMD, the level of 25-(OH)D, and bone turnover marker.
