Clinical analysis of depression, anxiety and sleep disorders in HIV/AIDS patients in Guangzhou
10.3760/cma.j.cn431274-20190126-00083
- VernacularTitle:广州市HIV/AIDS患者的抑郁、焦虑和睡眠障碍的临床分析
- Author:
Lizhi FENG
1
;
Pengle GUO
;
Haolan HE
;
Zhimin CHEN
;
Jiansheng ZHANG
;
Xuemei LING
;
Peishan DU
;
Weiping CAI
Author Information
1. 广州医科大学附属广州市第八人民医院感染病中心 510060
- From:
Journal of Chinese Physician
2020;22(4):481-485
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the characteristics and differences of anxiety, depression and sleep disorder among human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) patients in Guangzhou, then optimize the antiretroviral therapy and provide effective mental intervention.Methods:All HIV/AIDS patients from the outpatient department of Guangzhou Eighth People's Hospital were enrolled in the present study from January 2016 to December 2016. They were evaluated by the hospital anxiety and depression scale and Pittsburgh Sleep Quality Index, to analyze the levels of depression, anxiety and sleep disorder.Results:The incidences of anxiety, depression and sleep disorder were 30.5%(61/200), 31.0%(62/200) and 22.5%(45/200) respectively. 36.1%(22/61) of patients with anxiety and 35.5%(22/62) of patients with depression were accompanied by sleep disorder. The sleep disturbance index were significant higher in HIV/AIDS patients with anxiety ( t=4.065, P<0.001) or depression ( t=3.034, P=0.003) than those without anxiety or depression. Anxiety was mainly found in HIV/AIDS patients in aged 20 to 40 group ( F=7.998, P=0.018), while depression was mostly found in HIV/AIDS patients who didn't receive higher education ( F=13.55, P=0.001), and sleep disorder was more common in people with CD4 + count <200 cells/μl ( t=2.01, P=0.046). Conclusions:Anxiety and depression, which could aggravate sleep disorder, are very common in HIV/AIDS patients. Psychological care need to be strengthened to HIV positive patients in early phase, and screening questionnaires should be conducted before antiretroviral treatment began.
