Comparison of anesthetic effects and complications of different doses of ropivacaine in axillary brachial plexus block guided by ultrasound
10.3760/cma.j.cn431274-20190201-00107
- VernacularTitle:不同剂量罗哌卡因在超声引导下腋路臂丛神经阻滞中的麻醉效果
- Author:
Tianlei YU
1
;
Man LI
;
Ying LIU
Author Information
1. 四川省骨科医院麻醉科，成都 610041
- From:
Journal of Chinese Physician
2020;22(4):555-558
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the anesthetic effects and complications of different concentrations ropivacaine inultrasound-guided axillary brachial plexus block.Methods:From September 2016 to May 2018, 120 patients who underwent forearm or hand surgery in Sichuan Orthopedic hospital were selected as the study objects. According to the principle of random number table, the patients were divided into low-dose group ( n=40), medium dose group ( n=40) and high-dose group ( n=40). Different doses (0.25, 0.5, 0.75 ml/kg respectively) of 0.33% ropivacaine was used for local anesthesia. The anesthesia effect, complication rate, serum cardiac troponin I (cTnI) and creatine kinase myoglobin (CKMB) level and vital signs were compared among the three groups. Results:The onset time of sensory block and motor block in high dose group was shorter than that in low dose group and medium dose group, and the duration was longer than that in low dose group and medium dose group ( P<0.05); there was no significant difference in diastolic blood pressure (DBP), systolic blood pressure (SBP) and heart rate (HR) levels between the three groups at T 0 and T 3 ( P>0.05), and the DBP, SBP and HR levels in the three groups at T 1 were significantly lower than those at T 0 ( P<0.05); the level of DBP, SBP and HR in the low dose group was significantly higher than that in the medium dose group and the high dose group ( P<0.05), and there was no significant difference between the medium dose group and the high dose group ( P>0.05); the overall complication rate in the low dose group was 5.0%, which was significantly lower than that in the medium dose group (20.0%) and the high dose group (25.0%) ( P<0.05); after administration, the serum cTnI and CKMB levels in the low dose group were lower than those in the high dose group and medium dose group ( P<0.05). Conclusions:Three doses of ropivacaine can meet the surgical needs, but low-dose ropivacaine has a stable effect on vital signs and high safety.
