Application of propensity score method to analyze the effect of Maixuekang capsule on the treatment outcome of coronary heart disease
10.3760/cma.j.cn431274-20190213-00126
- VernacularTitle:应用倾向性评分方法分析脉血康胶囊对冠心病治疗结局的影响
- Author:
Renbo CHEN
1
;
Guozhong GAI
;
Wenli ZHANG
;
Yan ZHUANG
;
Yanming XIE
Author Information
1. 中国中医科学院中医临床基础医学研究所，北京 100700
- From:
Journal of Chinese Physician
2020;22(3):365-368
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the effect of Maixuekang Capsule on the treatment outcome of coronary heart disease (CHD) by propensity score.Methods:Based on the electronic medical record database of 22 large-scale tertiary hospitals nationwide, this study matched the coronary heart disease patients using and not using Maixuekang capsule according to a certain standard (1∶1). After matching, there were 2 464 cases in the patients group (group A) and the patients group (group B). In the database, the recombination of " recovery" and " improvement" is defined as effective treatment, and " invalid" , " death" and " other" are combined as ineffective treatment population. The effectiveness of the two groups after the re combination is compared by propensity score.Results:The results of χ 2 test showed that the difference between the two groups was statistically significant ( P<0.05) without controlling the confounding factors, and the treatment effect of group A was better than that of group B. In order to further observe the difference between the two groups, three logistic regression analysis methods were used to analyze, which showed that the regression coefficient was >0, and there was statistical significance ( P<0.01). Conclusions:The therapeutic effect of Maixuekang capsule on coronary heart disease is higher than that of patients without the drug.
