The direct effects and sustained effects of multi-task process cognitive training on cognitive function in the elderly with mild cognitive impairment
10.3760/cma.j.cn371468-20200604-01441
- VernacularTitle:多任务过程性认知训练对轻度认知障碍患者认知功能的直接效应与持续效应
- Author:
Xia ZHAO
1
;
Lina WANG
;
Chen ZHANG
;
Chenxi GE
;
Xiaoshen LIU
;
Xueting ZHEN
;
Feng WANG
;
Jie WANG
Author Information
1. 湖州师范学院护理学院 313000；苏州市广济医院临床精神科 215000
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2020;29(10):915-922
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the direct and sustained effects of multitask-process cognitive training program on cognitive function in the community elderly with mild cognitive impairment(MCI).Methods:Ninety-two participants with MCI who met the inclusion criteria were randomly selected from Huzhou community of Zhejiang province.According to the allocation ratio of 1∶1, the MCI participants were randomly divided into the cognitive training group and the control group, with 46 cases in each group.The participants in control group were received a cognitive function-health education program, and the participants in cognitive training group received an additional 10 weeks of multitask-process cognitive training.Respectively in three-time points of at baseline, after 10 weeks of training, and a 3-month follow-up to evaluate all participants with MCI executive function tested by trail making test A-B and Stroop color-word test, overall cognitive function tested by MoCA scale.Repeated measure ANOVA was used to compare the between-group variation, time effect and interaction effect of two groups at 3 time points.Results:The MoCA score of intervention group at T0, T1, T2 were 19.09±1.98, 21.09±1.41, 21.11±1.27 respectively, and the MoCA score of the control group were 18.24±2.22, 18.57±1.86, 18.07±1.90 respectively.Compared with the control group, the score of MoCA in the intervention group was significantly improved at T1 and T2 ( P< 0.05). Compared with control group, the Trail making test A-B, Stroop color-word interference test of intervention group were improved at T1, T2 ( P<0.05). Repeated measurement ANOVA shows that there were significant differences in Trail making test A-B, Stroop color-word interference test and MoCA between the two groups in terms of between-group effect, time effect and group-time interaction effect ( F=9.245~196.457, P<0.05). Simple effects analysis shows that compared with the control group, the multitask-process cognitive training had a positive direct effect on the Trail making test A-B, Stroop color-word interference test and MoCA, and these improvements maintained until the end of a 3-month follow-up ( F=2.757~201.829, P<0.05). During the research period, the compliance rate of the cognitive training group was 87.4%, and no adverse events occurred. Conclusion:The multitask-process cognitive training program positively promote the cognitive function of participants with MCI and provide a set of standardized and procedural nursing intervention program for the cognitive management of community participants with MCI.
