Effect of afternoon nap on cognitive function of patients with Alzheimer's disease and its related mechanisms
10.3760/cma.j.cn371468-20190927-00675
- VernacularTitle:午睡对阿尔茨海默病认知功能的作用及其相关机制
- Author:
Han CAI
1
;
Yuhua SHEN
;
Wei LI
;
Lin SUN
;
Shifu XIAO
Author Information
1. 芜湖市第四人民医院老年科 241000
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2020;29(5):471-474
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease (AD) is a degenerative disease of the central nervous system characterized by progressive cognitive and behavioral disorders.Clinical manifestations include memory impairment, aphasia, apraxia, impaired visual spatial function, executive power, decreased computing power, personality and behavior changes and so on.At present, the incidence of dementia is increasing year by year, causing a huge social burden, and there is still no effective treatment.Therefore, many scholars try to prevent and delay the occurrence of cognitive impairment through the identification and control of risk factors.Combining with previous studies, nap is helpful for the maintenance and consolidation of memory.This article discusses the effect of nap on cognitive function and its related mechanisms.First, nap can improve cognitive function, but it depends on the length, the frequency of the nap, and the difficulty of the task.Second, the effect of nap on cognition may be through inflammatory response, neuroendocrine, Aβ and gene polymorphism.In addition, this paper also proposes future research prospects in terms of standardized research methods, deepening research on relevant mechanisms, and lifestyle interventions in view of the lack of previous research.
