Research progress of coagulation dysfunction in coronavirus disease 2019
10.3760/cma.j.cn121430-20200426-00593
- VernacularTitle:新型冠状病毒肺炎凝血功能障碍相关研究进展
- Author:
Shengjian ZHONG
1
;
Fengfu WU
;
Na PENG
;
Qifeng XIE
;
Jingchun SONG
;
Weiqin LI
Author Information
1. 解放军联勤保障部队第九二三医院重症医学科，南宁 530021；武汉火神山医院，武汉 430071
- From:
Chinese Critical Care Medicine
2020;32(9):1135-1138
- CountryChina
- Language:Chinese
-
Abstract:
The coronavirus disease 2019 (COVID-19) has outbroken globally. As an acute infectious disease, COVID-19 has significant impacts on multiple organs and systems throughout the body. Among patients with COVID-19, especially severe and critical cases, a variety of potential risk factors for coagulation dysfunction exist. Furthermore, the coagulation dysfunction of COVID-19 patients was mainly characterized by elevated D-dimer levels. The coagulation dysfunction could directly affect the prognosis of COVID-19 patients and is a major cause of death in patients with severe COVID-19. In this article, the literatures on the basic clinical manifestations, clinical risk factor, mechanism of coagulation dysfunction and evaluation of coagulation function in COVID-19 were reviewed.
