Research progress on the mechanism of pro-inflammatory regression mediators promoting inflammation regression by regulating immune cells
10.3760/cma.j.cn121430-20200224-00196
- VernacularTitle:促炎症消退介质通过调节免疫细胞促进炎症消退的机制研究进展
- Author:
Jingxu WANG
1
;
Haifa XIA
;
Shanglong YAO
Author Information
1. 华中科技大学同济医学院附属协和医院麻醉科，麻醉与危重病研究所，武汉 430022
- From:
Chinese Critical Care Medicine
2020;32(7):873-876
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory response is an effective host defense mechanism to eliminate pathogens at the site of infection. The regression phase of inflammation mainly maintains the stable environment in tissues. Pro-inflammatory regression mediators (SPMs) are endogenous anti-inflammatory molecules, which play an important role in reducing excessive tissue damage and chronic inflammation. This paper reviews the interaction between SPMs and immune cells in inflammatory sites. By reviewing the relevant literature, it was found that SPMs regulate the components of innate and adaptive immune system, including neutrophils, macrophages, innate lymphocytes, natural killer cells and T cells.
