Application of convalescent plasma for the treatment of adult patients with coronavirus disease 2019
10.3760/cma.j.cn121430-20200601-00479
- VernacularTitle:恢复期血浆在新型冠状病毒肺炎成人患者治疗中的应用
- Author:
Shuangling LI
1
;
Hong ZHAO
;
Yueming SUN
;
Peng WANG
;
Haixia LI
;
Meili DUAN
Author Information
1. 北京大学第一医院重症医学科,北京 100034
- From:
Chinese Critical Care Medicine
2020;32(6):646-651
- CountryChina
- Language:Chinese
-
Abstract:
The high incidence of coronavirus disease 2019 (COVID-19) and high mortality of critical patients have posed a great challenge to global public health resources. Currently there are no specific antiviral drugs and vaccines available for COVID-19, which has drawn the attention to the usefulness of convalescent plasma (CP) again, so the application of CP in the adult patients with COVID-19 is reviewed. The main contents include the possible mechanism of CP, the evidence of CP in the treatment of COVID-19 patients, the safety of clinical application of CP and the main factors affecting the clinical effect of CP, which may provide some basis for clinicians to choose CP for the treatment of adult patients with COVID-19.