An equation for calculating the osmolarity of adult total nutrient admixture

VernacularTitle:一种成人肠外营养液渗透压摩尔浓度预测公式的建立
Author: Xiaoqin LANG ¹ ; Boyu LU ; Xue BAI ; Jiaqiang XU ; Bin ZHAO ; Dan MEI
Author Information

1. 中国医学科学院　北京协和医学院　北京协和医院药剂科　100730；解放军陆军军医大学第一附属医院药剂科，重庆　400038
From: Chinese Journal of Clinical Nutrition 2020;28(2):87-92
CountryChina
Language:Chinese
Abstract: Objective:To establish a predictive equation for the osmolarity of parenteral nutritional prescription in China.Methods:From July 2019 to September 2019, 2 480 individualized samples of 328 different parenteral nutritional prescriptions (adult) of Peking Union Medical College Hospital were collected, and the osmolarity of parenteral nutritional solution samples was determined by a freezing point reduction method. Pearson χ2 test and a multiple linear regression analysis were utilized to establish a prediction equation for the osmolality of parenteral nutritional solution. Results:The average osmolarity of parenteral nutritional prescription was (1 164.20 ± 252.59) mOsm/kg, and the best fitting equation was (9.66A+ 7.88G+ 3.52F+ 36.4Na+ 27.55K+ 3.38P+ 7.46W-250)/V.Conclusion:The osmolarity is determined accurately and effectively by the fitting equation, which provide a benefit reference for the formulation, review and selection of clinical parenteral nutrition prescription especially in China.