Comparative study of the effects of laparoscopic and open colorectal cancer surgery on intestinal barrier function
10.3760/cma.j.cn115822-20190114-00003
- VernacularTitle:腹腔镜与开腹结直肠癌手术对肠道屏障功能影响的比较研究
- Author:
Yuntong GUO
1
;
Wei LIU
;
He HUANG
Author Information
1. 山西医科大学第一医院普外科 , 太原 030001
- From:
Chinese Journal of Clinical Nutrition
2020;28(1):27-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare and investigate the effects of laparoscopy and open colorectal cancer on the intestinal barrier function in patients with colorectal cancer.Methods:Sixty-two patients with colorectal cancer admitted in our hospital from January 2015 to October 2016 were selected and divided into laparoscopic surgery group with thirty-four patients and open surgery group with twenty-eight patients. The changes of postoperative intestinal barrier function were compared between the two groups.Result:The levels of plasma D-lactate, plasma diamine oxidase (DAO) and bacterial endotoxin in the laparoscopic surgery group were significantly lower than those in the open surgery group ( P<0.05). Conclusion:Laparoscopic and open colorectal cancer surgery can cause damage to intestinal barrier function, but the damage of laparoscopic colorectal cancer surgery is lower than that of open colorectal surgery.
