Clinical effects of traditional Chinese medicine fumigation-washing therapy combined with etofenamate cream in the treatment of mild and moderate knee osteoarthritis
10.3760/cma.j.issn.1008-6706.2020.19.011
- VernacularTitle:中药熏洗联合依托芬那酯凝胶治疗轻中度膝骨关节炎的疗效观察
- Author:
Peng CHENG
1
;
Yongxiang LUO
;
Anmin CHEN
Author Information
1. 华中科技大学同济医学院附属同济医院骨科，武汉 430030
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(19):2353-2356
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical effect of traditional Chinese medicine(TCM) fumigation-washing therapy combined with etofenamate cream wiping in the treatment of knee osteoarthritis.Methods:From September 2018 to April 2019, 176 cases of knee osteoarthritis were divided into two groups according to random number table method.The observation group (91 cases) was treated by etofenamate cream based on fumigation-washing therapy with TCM, while the control group (85 cases) was treated by etofenamate cream wiping only.Both two groups continued treatment for 2 weeks.The Lequesne score and effective rate of the two groups were achieved and analyzed.Results:At 1 d and 2 weeks after treatment, there were no statistically significant differences in the Lequesne score between the two groups(all P>0.05). After treatment for 1 month and 3 months, Lequesne scores of the observation group[(4.1±1.1)points, (4.6±1.0)points] were lower than those of the control group [(6.2±1.2)points, (7.5±1.4)points]( t=12.155, 15.598, all P<0.05). At 1 d and 2 weeks after treatment, there were no statistically significant difference in the effective rate between the two groups(all P>0.05). After treatment for 1 month and 3 months, the effective rates of the observation group were 63.7%(58/91) and 61.5%(56/91), respectively, which were higher than those of the control group [41.2%(35/85) and 18.8%(16/85)] (χ 2=8.98, 33.17, all P<0.05). Conclusion:Fumigation-washing therapy with TCM combined with etofenamate cream wiping has quick, lasting and safe effect in the treatment of knee osteoarthritis.
