Biopsy pathological analysis of 220 cases of cervical cytology negative and high-risk HPV positive
10.3760/cma.j.issn.1008-6706.2020.18.016
- VernacularTitle:宫颈细胞学筛查阴性、高危型人乳头瘤病毒检查阳性患者220例病理检查分析
- Author:
Yanmin ZHOU
1
;
Huiya ZHANG
;
Xiaohua MENG
;
Junxia CHEN
Author Information
1. 绍兴市人民医院 浙江大学绍兴医院妇科 312000
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(18):2245-2248
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical significance of biopsy pathological examination of cervical cytology negative, high-risk human papillomavirus (HPV) positive.Methods:The pathological data of cervical biopsy in 220 patients with cytological negative, HPV16/18 positive or interval of 1 year other 12 high-risk HPV (12HR-HPV) lasting positive for more than 1 year from January 2014 to May 2019 were retrospectively analyzed.Results:Of 220 patients, there were 3 cases with adenocarcinoma, 18 cases with CINⅢ, 18 cases with CINⅡ, 69 cases with CINⅠ, 47 cases with condyloma-like lesions, 65 cases of chronic inflammation.Among 36 cases of high-grade squamous intraepithelial lesions, there were 35 cases with HPV16/18 positive, accounting for about 15.91%(35/220), and only 1 case of other 12 high-risk HPV was continuously positive for more than one year, accounting for 0.45%(1/220).Conclusion:Cervical cytological screening may appear false negative, high-risk HPV typing examination may be more able to detect cervical intraepithelial lesions, for cytological negative, high-risk HPV positive, especially HPV16/18 positive, immediate referral colposcopy can reduce the missed diagnosis of cervical high-grade squamous intraepithelial lesions and even cancerous.
