Analysis of effect of acupoint sticking combined with Bushen Yiqi and Guchong Antai decoction in the treatment of threatened abortion with kidney deficiency
10.3760/cma.j.issn.1008-6706.2020.14.008
- VernacularTitle:穴位贴敷联合补肾益气固冲安胎汤辅助治疗肾虚型先兆流产的效果分析
- Author:
Huijun ZHENG
1
;
Yun SUN
;
Dazheng MA
Author Information
1. 浙江省,温州市中医院中医妇科 325000
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(14):1698-1702
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical effects of acupoint sticking combined with Bushen Yiqi and Guchong Antai decoction in the treatment of threatened abortion with kidney deficiency.Methods:From June 2018 to February 2019, 80 patients with threatened abortion and kidney deficiency type in Wenzhou Hospital of Traditional Chinese Medicine were selected and divided into observation group and control group according to the random digital table method, with 40 cases in each group.The control group was given progesterone injection, while the observation group received acupoint sticking combined with Bushen Yiqi and Guchong Antai decoction on the basis of the control group.Both two groups were treated for 2 weeks.Before and after treatment, the improvement of clinical symptoms, the levels of sex hormones[serum progesterone(P), estradiol(E 2), human chorionic gonadotropin(β-HCG), progesterone-induced blockade factor(PIBF)] and lymph immune cells were recorded and compared in the two groups, and the clinical efficacy was evaluated. Results:After treatment, the vaginal bleeding, lumbosacral soreness, bleeding time, burnout symptoms and total scores in the two groups were all decreased significantly compared with those before treatment( t≥29.780, all P<0.05), which of the observation group decreased more significantly( t=11.655, 10.864, 8.898, 1.910, 17.415, all P<0.055). The total effective rate in the observation group was 95.00%(38/40), which was significantly higher than 70.00%(28/40) in the control group(χ 2=5.854, P<0.05). After treatment, the levels of P, E 2, β-HCG and PIBF increased significantly in the two groups( t≥5.507, all P<0.05), but the increasing degrees in the observation group were more significant( t=6.358, 16.297, 112.692, 3.262, all P<0.05). After treatment, the levels of CD 4+ and NK in the observation group were significantly lower than those before treatment( t=12.538, 4.520, all P<0.05), and the level of CD 8+ in the observation group was significantly higher than that before treatment( t=6.982, P<0.05), but the above indicators in the control group before and after treatment had no statistically significant differences( t=0.769, 1.594, 1.292, all P>0.05). Conclusion:Acupoint sticking combined with Bushen Yiqi and Guchong Antai decoction can significantly improve the clinical symptoms of threatened abortion women, which has better clinical effects, and its mechanism may be related to the regulation of hormone levels and chronic inflammatory status in pregnant women.