Clinical value of sevoflurane inhalation combined with epidural anesthesia in elderly patients with digestive tract malignant tumors
10.3760/cma.j.issn.1008-6706.2020.13.008
- VernacularTitle:七氟烷吸入联合硬膜外麻醉在老年人消化道恶性肿瘤手术中的价值分析
- Author:
Guangfeng ZHU
1
Author Information
1. 浙江省，温州市中西医结合医院麻醉科 325000
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(13):1569-1572
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical value of sevoflurane inhalation combined with epidural anesthesia in the operation of digestive tract malignant tumors in the elderly.Methods:From August 2016 to September 2017, 74 elderly patients with digestive tract malignant tumors who were operated in the Integrated Traditional Chinese and Western Medicine Hospital of Wenzhou were divided into two groups by random number table method, with 37 cases in each group.The control group was given sevoflurane inhalation anesthesia, while the observation group was given sevoflurane inhalation combined with epidural anesthesia.The changes of blood pressure, heart rate and cognitive function were observed.Results:There were no statistically significant differences in blood pressure and heart rate between the two groups at 5 minutes after tracheal intubation (all P>0.05). After 0 and 10 min of recovery of bilateral lung ventilation, the blood pressures of the observation group were (74.75±4.93)mmHg, (72.79±4.60)mmHg, respectively, which were lower than those of the control group [(82.44±3.62)mmHg, (75.70±5.14)mmHg] ( t=7.648, 2.562, all P<0.05). The heart rate of recovery of bilateral pulmonary ventilation in the observation group was (70.75±4.21) times/min, which in the control group was (75.91±3.89)times/min, the difference was statistically significant between the two groups( t=5.476, P<0.05). The cognitive function scores of the observation group were (25.74±0.69)points, (26.13±1.49)points, (27.90±0.77)points, (28.26±1.18)points, respectively, which were higher than those of the control group [(19.88±2.30)points, (22.85±0.96)points, (24.38±1.21)points, (24.35±1.63)points] ( t=14.844, 11.256, 14.929, 11.819, all P<0.05). Conclusion:Sevoflurane inhalation combined with epidural anesthesia is effective for elderly patients with digestive tract malignant tumors, which can avoid excessive fluctuation of physical signs and promote the recovery of cognitive function.
