Value of diagnostic plaque of type and nature in patients with coronary atherosclerotic heart disease by coronary CT angiography
10.3760/cma.j.issn.1008-6706.2020.10.006
- VernacularTitle:冠状动脉CT血管造影对冠状动脉粥样硬化性心脏病患者斑块类型及性质的诊断价值
- Author:
Xiuxiu ZHANG
1
;
Weiping ZHU
;
Yuqing LIAN
;
Mingbin XIE
Author Information
1. 杭州市红十字会医院放射科 310003
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(10):1177-1180
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the diagnostic value of plaque type and nature of coronary artery angiography in patients with coronary heart disease.Methods:The clinical data of 80 patients with coronary heart disease in Hangzhou Red Cross Hospital were retrospectively analyzed.According to the CT value of plaque, 20 cases were classified into calcified plaque group (CT value ≥130 HU) and soft plaque group (CT value ≤60 HU). Mixed plaque group (CT value 60-130 HU) had 40 cases.The association between coronary stenosis and plaque type, platelet function, serum biochemical and adipocytokine indicators were compared among the three groups.Results:There was a certain correlation between the proportion of different types of plaque and the degree of stenosis.There were 12 cases of mild stenosis, 3 cases of moderate stenosis and 5 cases of severe stenosis in calcified plaque group, 11 cases of mild stenosis, 14 cases of moderate stenosis and 15 cases of severe stenosis in mixed plaque group, 2 cases of mild stenosis, 7 cases of moderate stenosis and 11 cases of severe stenosis in soft tissue plaque group, the difference was statistically significant (χ 2=13.27, P<0.05). Comparison of platelet function, the calcified plaque group, mixed plaque group and soft tissue plaque group had no statistically significant difference in platelet count (PLT) ( F=1.56, P>0.05). The PDGF-BB, TEG-MA and P-selectin levels in the soft tissue plaque group were higher than those in the mixed plaque group and the calcified plaque group, the differences were statistically significant ( F=11.57, 6.47, 18.74, all P<0.05). As to the adipose cytokines, the levels of CRP, IL-6, IL-12, leptin and SFRP5 in the soft tissue plaque group were higher than those in the mixed plaque group and the calcified plaque group, the differences were statistically significant( F=7.95, 21.31, 14.58, 9.37, 13.58, all P<0.05). Conclusion:Coronary CT angiography can evaluate the severity of coronary heart disease by evaluating the type of plaque, and provide a theoretical basis for clinical treatment.It is worthy of clinical promotion.
