Analysis of risk factors of positive surgical margin and residual lesions after cone resection of high-grade intraepithelial neoplasia
10.3760/cma.j.issn.1008-6706.2020.06.001
- VernacularTitle:宫颈高级别上皮内瘤变锥切术后切缘阳性及再次手术病灶残留的危险因素分析
- Author:
Ruili DONG
1
;
Ya′nan JI
Author Information
1. 内蒙古自治区人民医院妇产科，呼和浩特 010017
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(6):641-645
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the risk factors of positive surgical margin and residual lesions after cone resection of high-grade intraepithelial neoplasia, and to guide clinical work and follow-up.Methods:The clinical data of 180 patients with cervical epithelial neoplasia of grade Ⅱ and Ⅲ who underwent cervical conization in the People's Hospital of Inner Mongolia Autonomous Region from November 2013 to November 2018 were retrospectively analyzed.The risk factors associated with residual margin and reoperation (including re-cone and hysterectomy) after conization were performed by single factor and multivariate regression analysis.Results:The incidence of positive resection margins after conization was 31.67%(57/180), which of the residual margin of re-surgery was 36.84%(21/57). Menopause, contact bleeding, cervical cancer(in situ carcinoma, microinvasive carcinoma) were positive risk factors for conical cutting margin ( OR=2.342, 2.428, 8.949). Contact bleeding, cervical cancer(in situ carcinoma, microinvasive carcinoma) were risk factors for residual resection of the surgical margin after conization ( OR=5.370, 10.992). Conclusion:Contact bleeding, cervical carcinoma in situ, microinvasive carcinoma are closely related to cervical margin and lesion residual.Among them, menopause is also positively related to margin, which is a risk factor affecting cervical cone cutting margin and residual reoperation.It should be highly valued in clinical.
