Therapeutic effect of acitretin combined with traditional Chinese Medicine on pustular psoriasis
10.3760/cma.j.issn.1008-6706.2020.05.013
- VernacularTitle:阿维A联合中药治疗脓疱型银屑病疗效观察
- Author:
Linghua QIN
1
Author Information
1. 山西省，长治市第二人民医院皮肤科 046000
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(5):568-571
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the efficacy of acitretin combined with traditional Chinese medicine in the treatment of pustular psoriasis.Methods:From July 2011 to October 2017, 91 patients with pustular psoriasis admitted to the Second People's Hospital of Changzhi were randomly divided into treatment group( n=31), control group Ⅰ ( n=30) and control group Ⅱ(n=30) according to the digital table.The patients in the three groups were treated with acitretin combined with traditional Chinese medicine, oral acitretin and traditional Chinese medicine, respectively.The therapeutic effects, the time required for hypothermia, the time required for the complete disappearance of pustules and the average length of hospitalization were compared among the three groups. Results:The total effective rate was 93.55%(29/31) in the treatment group, 70.00%(21/30) in the control group Ⅰ and 73.33%(22/30) in the control group Ⅱ.The total effective rate in the treatment group was significantly higher than that in the two control groups(χ 2=5.720, 4.546, all P<0.05). There was no statistically significant difference in total effective rate between the control group Ⅰ and the control group Ⅱ( P>0.05). The fever allaying time, completely disappearance time of pustules, average hospital stay in the treatment group were (4.24±0.86)d, (7.38±0.72)d, (23.46±0.61)d, respectively, which in the control group Ⅰ were (7.45±0.92)d, (10.45±0.52)d, (30.01±0.82)d, respectively, which in the control group Ⅱ were (8.56±0.78)d, (11.56±0.35)d, (31.53±0.68)d, respectively, which in the control group Ⅰ were significantly shorter than those in the control group Ⅱ( t=14.083, 19.037, 35.476, all P<0.05), which in the treatment group were significantly lower than those in the control group Ⅰ and the control group Ⅱ( t=20.529, 28.682, 48.826, 5.041, 9.699, 7.816, all P<0.05). Conclusion:Acitretin capsule combined with traditional Chinese medicine is effective in the treatment of pustular psoriasis, which can control body temperature in a short time, shorten the time of disappearance of pustule, relieve the pain of patients, and shorten the time of hospitalization at the same time.
