Research progress between hypoxia inducible factors and osteoarthritis
10.3760/cma.j.issn.2095-4255.2020.02.017
- VernacularTitle:低氧诱导因子与骨关节炎关系的研究进展
- Author:
Hongting SHEN
1
;
Mingjun WANG
;
Qiang LI
;
Zhijun ZHAO
Author Information
1. 青海省地方病预防控制所地方病预防控制科，西宁 811602
- From:
Chinese Journal of Endemiology
2020;39(2):154-156
- CountryChina
- Language:Chinese
-
Abstract:
Hypoxia-inducible factors (HIFs) play an important role in development, formation, regeneration and metabolism of extracellular matrix among bone and cartilage. Osteoarthritis (OA) is caused by many reasons, which result in degeneration and damage of joint cartilage and reaction regeneration of joint margin and subchondrobone. The etiology of OA remains uncertain; the relationship between HIFs and OA could provide scientific data for OA prevention and control.
