Advances in the pathogenesis of articular cartilage injury in Kaschin-Beck disease
10.3760/cma.j.issn.2095-4255.2020.02.016
- VernacularTitle:大骨节病关节软骨损伤发病机制研究进展
- Author:
Yun CAI
1
;
Xianhao WU
;
Liyan SUN
Author Information
1. 哈尔滨医科大学中国疾病预防控制中心地方病控制中心大骨节病防治研究所 150081
- From:
Chinese Journal of Endemiology
2020;39(2):150-153
- CountryChina
- Language:Chinese
-
Abstract:
Kaschin-Beck disease (KBD) is an endemic and deforming osteochondropathy, and its pathogen and pathogenesis remain unclear up to now. In recent years, the results in the research of pathogenesis of KBD showed that oxidative stress, excessive chondrocyte apoptosis, imbalance of chondrocyte extracellular matrix metabolism and pro-inflammatory factors were all involved in the occurrence and development of KBD. And this paper summarized the important progress in the pathogenesis of KBD.
