Clinical value of Yiqi Wenyang Huoxue Recipe in treating chronic cor pulmonale
10.3760/cma.j.cn115455-20200414-00471
- VernacularTitle:益气温阳活血方治疗慢性肺源性心脏病的临床价值
- Author:
Fei WANG
1
;
Tianxiong HAN
;
Lei WANG
Author Information
1. 上海市第十人民医院中医科 200072
- From:
Chinese Journal of Postgraduates of Medicine
2020;43(8):720-724
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical value of Yiqi Wenyang Huoxue Recipe in the treatment of chronic cor pulmonale.Methods:Sixty patients with clinical criteria of chronic pulmonary heart disease were collected and divided into treatment group and control group according to the random numbers table, of which 30 cases were in the treatment group and 30 cases were in the control group. In the treatment group, 30 cases were treated with routine drug treatment plus Yiqi Wenyang Huoxue Fang created by Professor Yandexin. In control group, 30 patients underwent routine treatment. The levels of left ventricular ejection fraction (LVEF), B-natriuretic peptide (BNP), Forced expiratory volume in one second (FEV 1)/Forced expiratory volume (FVC) and quality of life score of the two groups were compared. Results:After treatment, the BNP in the treatment group was lower than that in the control group [(218.50 ± 25.64) ng/L vs. (211.60 ± 29.51) ng/L], the LVEF in the treatment group was higher than that in the control group [(58.83 ± 3.16)% vs. (52.80 ± 4.23)%], FEV 1/FVC and quality of life score were higher than those in the control group [(89.13 ± 3.44) scores vs. (76.90 ± 3.79) scores, (79.27 ± 5.71) scores vs. (70.30 ± 5.49) scores], and there were significant differences ( P<0.05). There were no significant changes in kidney function, coagulation function and electrocardiogram in treatemnt group before and after treatment. Conclusions:Treatment of chronic cor pulmonale with traditional Chinese medicine Yiqi Wenyang Huoxue on the basis of conventional western medicine can significantly improve the clinical curative effect of the disease, reduce the burden on the heart and improve the quality of life.
