Clinical characteristics and treatment of pituitary thyrotropin mixed secreting adenoma
10.3760/cma.j.cn115455-20200305-00239
- VernacularTitle:垂体促甲状腺激素混合型腺瘤的临床特点和治疗
- Author:
Jian XU
1
;
Chunfang ZHANG
;
Hong FAN
;
Liyong ZHONG
Author Information
1. 首都医科大学附属北京天坛医院内分泌科 100160
- From:
Chinese Journal of Postgraduates of Medicine
2020;43(7):655-658
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the clinical characteristics and treatment of pituitary thyrotropin mixed secreting adenoma.Methods:The clinical data of 9 patients with pituitary thyrotropin mixed secreting adenoma from January 2008 to December 2019 in Beijing Tiantan Hospital, Capital Medical University, were retrospectively analyzed.Results:Among 9 patients, male was in 7 cases, and female in 2 cases; age was (35.7 ± 13.5) years; course of disease was (3.8 ± 3.1) years; mixed thyrotropin and growth hormone secreting adenoma was in 6 cases; most of them were accompanied with different degrees of thyrotoxicosis, 6 with acromegaly and 2 with amenorrhea and lactation. All the tumors were pituitary macroadenoma, with aggressive growth. Only 1 patient was completely relieved after operation, and most patients needed combined treatment to control the disease.Conclusions:Mixed thyrotropin and growth hormone secreting adenoma is the most common type of the disease, the clinical manifestations are complex, and the tumor is aggressive growth, surgical treatment can not be completely relieved and radiotherapy and/or combination of medicine treatment can help to improve the condition.
