Effect of high flow nasal catheter ventilation in mechanical ventilation withdrawal of premature infants and its influence on blood gas analysis
10.3760/cma.j.cn115455-20191011-00773
- VernacularTitle:早产儿高流量鼻导管通气在机械通气撤机中的效果及对血气分析的影响
- Author:
Fan WANG
1
;
Gesheng WEN
;
Qi JIANG
Author Information
1. 浙江省湖州市妇幼保健院新生儿科 313000
- From:
Chinese Journal of Postgraduates of Medicine
2020;43(5):444-447
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of high flow nasal catheter ventilation (HFNC) in mechanical ventilation withdrawal of premature infants and its influence on blood gas analysis.Methods:The clinical data of 60 premature infants with mechanical ventilation from January 2017 to December 2018 in Huzhou Maternal and Child Health Hospital were analyzed retrospectively. After withdrawal, 30 premature infants treated with nasal continuous positive airway pressure (NCPAP) were as NCPAP group, and 30 premature infants treated with HFNC were as HFNC group. The ventilation time, total oxygen use time, complications, and arterial partial pressure of oxygen (PaO 2) and arterial partial pressure of carbon dioxide (PaCO 2) 12 and 24 h after withdrawal were compared between 2 groups. Results:There were no statistical differences in ventilation time and total oxygen use time between 2 groups ( P>0.05). The incidence of complications in HFNC group was significantly lower than that in NCPAP group: 13.33% (4/30) vs. 46.67% (14/30), and there was statistical difference ( P<0.05). The PaO 2 12 and 24 h after withdrawal in HFNC group was significantly higher than that in NCPAP group: (68.83 ± 2.76) mmHg (1 mmHg=0.133 kPa) vs. (64.79 ± 2.31) mmHg and (78.46 ± 3.32) mmHg vs. (74.72 ± 2.18) mmHg, the PaCO 2 was significantly lower than that in NCPAP group: (48.93 ± 2.51) mmHg vs. (52.31 ± 3.18) mmHg and (38.78 ± 4.23) mmHg vs. (43.67 ± 3.65) mmHg, and there were statistical differences ( P<0.05). Conclusions:HFNC is effective in mechanical ventilation withdrawal of premature infants, which can reduce complications and improve blood gas analysis.
