Research progress in treatment for advanced gastric cancer
10.3760/cma.j.cn115610-20200804-00531
- VernacularTitle:晚期胃癌治疗的研究进展
- Author:
Xinhua CHEN
1
;
Zhousheng LIN
;
Yuehong CHEN
;
Tao LI
;
Jiang YU
Author Information
1. 南方医科大学南方医院普通外科，广州 510515
- From:
Chinese Journal of Digestive Surgery
2020;19(10):1111-1118
- CountryChina
- Language:Chinese
-
Abstract:
The prognosis of advanced gastric cancer (AGC) is extremely poor. There is no standard and satisfactory treatment strategy for AGC. In clinical practice, some AGC patients can achieve long-term survival. However, it is not clear which type of AGC can benefit the best in specific treatment mode. Because of the high heterogeneity of AGC, it is particularly important to further dig out more significant beneficiary groups. Therefore, experts put forward the classification based on the biological characteristics and the surgery-oriented classification to predict and select patients who benefit from conversion therapy. While for immunotherapy, the biomarkers, molecular subtyping and potential combination strategies are explored to break through its bottleneck in the treatment in AGC that only certain individuals benefit from it. The authors review the research progress in treatment for advanced gastric cancer.
