The Clinical Profile of Patients with Psoriasis in Korea: A Nationwide Cross-Sectional Study (EPI-PSODE).
- Author:
Hae Jun SONG
1
;
Chul Jong PARK
;
Tae Yoon KIM
;
Yong Beom CHOE
;
Seok Jong LEE
;
Nack In KIM
;
Jae We CHO
;
Jie Hyun JEON
;
Min Soo JANG
;
Jai Il YOUN
;
Myung Hwa KIM
;
Joonsoo PARK
;
Ki Ho KIM
;
Byung Soo KIM
;
Sang Woong YOUN
;
Joo Heung LEE
;
Min Geol LEE
;
Sung Ku AHN
;
Young Ho WON
;
Seok Kweon YUN
;
Bong Seok SHIN
;
Seong Jun SEO
;
Ji Yeoun LEE
;
Kwang Joong KIM
;
Young Suck RO
;
Youngdoe KIM
;
Dae Young YU
;
Jee Ho CHOI
Author Information
- Publication Type:Multicenter Study ; Original Article
- Keywords: Epidemiologic studies; Korea; Psoriasis
- MeSH: Adult; Biological Products; Blood Pressure; Body Mass Index; Body Surface Area; Cross-Sectional Studies*; Diagnosis; Epidemiologic Studies; Epidemiology; Female; Hospitals, University; Humans; Korea*; Phototherapy; Psoriasis*; Waist Circumference
- From:Annals of Dermatology 2017;29(4):462-470
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: Psoriasis is an immune-mediated, chronic inflammatory disease affecting multiple aspects of patients' lives. Its epidemiology varies regionally; however, nationwide epidemiologic data on psoriasis depicting profile of Korean patients has not been available to date. OBJECTIVE: To understand nationwide epidemiologic characteristics and clinical features of adult patients with psoriasis visited university hospitals in Korea. METHODS: This multicenter, non-interventional, cross-sectional study recruited 1,278 adult patients with psoriasis across 25 centers in Korea in 2013. Various clinical data including PASI, BSA, DLQI, SF-36 and PASE were collected. RESULTS: A total of 1,260 patients completed the study (male:female=1.47:1). The mean age was 47.0 years with a distribution mostly in the 50s (24.9%). Early onset (<40 years) of psoriasis accounted for 53.9% of patients. The mean disease duration was 109.2 months; mean body mass index was 23.9 kg/m²; and 12.7% of patients had a family history of psoriasis. Plaque and guttate types of psoriasis accounted for 85.8% and 8.4%, respectively. Patients with PASI ≥10 accounted for 24.9%; patients with body surface area ≥10 were 45.9%. Patients with DLQI ≥6 accounted for 78.8%. Between PASI <10 and PASI ≥10 groups, significant difference was noted in age at diagnosis, disease duration, blood pressure, waist circumference of female, and treatment experiences with phototherapy, systemic agents, and biologics. CONCLUSION: This was the first nationwide epidemiologic study of patients with psoriasis in Korea and provides an overview of the epidemiologic characteristics and clinical profiles of this patient population.
