The significance of advanced glycation end-product receptors in sepsis organ damage
10.3760/cma.j.issn.1673-4912.2020.10.011
- VernacularTitle:晚期糖基化终产物受体在脓毒症器官功能损伤中的意义
- Author:
Yipei LI
1
;
Chunfeng LIU
Author Information
1. 中国医科大学附属盛京医院小儿内科，沈阳 110004
- From:
Chinese Pediatric Emergency Medicine
2020;27(10):762-766
- CountryChina
- Language:Chinese
-
Abstract:
It is one of the ten leading causes of death worldwide and has become one of the leading causes in children.The receptor for advanced glycation end products (RAGE) is a membrane protein that belongs to the immunoglobulin superfamily.Recently, studies have shown that RAGE can be involved in sepsis induced myocardial injury, kidney injury, lung injury, abnormal coagulation function, liver injury and neuropathy, which is closely related with the development and prognosis of sepsis.
