Application of nasal continuous positive airway pressure ventilation in congenital airway stenosis with pneumonia: a 5-year single-center retrospective study
10.3760/cma.j.issn.1673-4912.2020.08.011
- VernacularTitle:经鼻持续气道正压通气在先天性气道狭窄合并肺炎中的应用：5年单中心回顾性研究
- Author:
Nan HE
1
;
Jian JI
;
Suyun QIAN
;
Hengmiao GAO
;
Jiansheng ZENG
;
Jun LIU
;
Zheng LI
Author Information
1. 国家儿童医学中心 首都医科大学附属北京儿童医院重症医学科 100045；首都医科大学附属北京潞河医院儿科 101149
- From:
Chinese Pediatric Emergency Medicine
2020;27(8):614-617
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy and safety of nasal continuous positive airway pressure(NCPAP) in the treatment of congenital airway stenosis with severe pneumonia.Methods:A single-center retrospective clinical study was used to select children with congenital airway stenosis and pneumonia who were admitted to PICU of Beijing Children′s Hospital of Capital Medical University during 5 years and treated with NCPAP within 48 hours after admission.The baseline data, clinical manifestations, vital signs, arterial blood gas, clinical outcomes, NCPAP use time and adverse reactions were collected.Results:A total of 64 children were included in this study, with 58 cases in the effective group and six cases in the ineffective group.The total effective rate of NCPAP was 90.6% (58/64) during 5 years.In the effective group, 63.8% patients were weaned in three to seven days, with an average weaning time of 6.09 days.In the effective group, the heart rate and PaCO 2 after NCPAP treatment were significantly lower than that before treatment, and pH and PaO 2 were significantly higher than that before treatment, and the difference was statistically significant (all P<0.05). A total of six patients in the ineffective group were finally changed to tracheal intubation and invasive ventilation.The survival rate of both groups was 100%.All cases had no adverse reactions or complications. Conclusion:NCPAP can effectively improve the oxygenation in children with congenital airway stenosis and severe pneumonia, with high efficiency and good safety.
