Progress in the study of Down′s syndrome complicated with acute lymphoblastic leukemia
10.3760/cma.j.cn101070-20190413-00312
- VernacularTitle:唐氏综合征并急性淋巴细胞白血病研究进展
- Author:
Zirui GAO
1
;
Huimin ZENG
Author Information
1. 北京大学人民医院儿科 100044
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(22):1751-1754
- CountryChina
- Language:Chinese
-
Abstract:
Down′s syndrome(DS), also known as Trisomy 21 syndrome, is associated with a variety of blood system diseases, including transient blood cell count abnormalities in newborns, transient myeloproliferative diseases, and acute and chronic leukemia.In this article, the pathogenesis of blood system abnormalities in children with DS was reviewed, and research progress in children with DS and acute lymphoblastic leukemia was summarized from the aspects of clinical and biological characteristics, treatment and prognosis.
