Research advances in the role of ion channels genetics in autism spectrum disorders
10.3760/cma.j.cn101070-20190816-00755
- VernacularTitle:孤独症谱系障碍相关离子通道基因研究进展
- Author:
Kanghui LI
1
;
Zhaohui WANG
Author Information
1. 西安市第四医院儿童保健科 710000
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(20):1597-1600
- CountryChina
- Language:Chinese
-
Abstract:
Autism spectrum disorder (ASD) are kind of developmental behavior disorders with the core symptoms of social communication disorders, stereotyped behavior and narrow interest.Genetic factors play an important role in the incidence of ASD.Ion channels are a pore-forming protein on biofilm.They allow certain types of ions to pass through, and help to establish the voltage difference between cytoplasmic membranes, acting as the basis of neuroelectrophysiology.Ion channel abnormalities are related to many diseases, including ASD.In this paper, several kinds of genes related to ASDs in ion channels were reviewed, and in order to provide new ideas in the pathogenesis.
