Liver transplantation for treatment of mushroom poisoning complicated with multiple organ dysfunction syndrome : a case report and literature review
10.3760/cma.j.cn101070-20190821-00778
- VernacularTitle:肝移植治疗儿童毒蕈中毒并多脏器衰竭1例并文献复习
- Author:
Xiyan TIAN
1
;
Yufeng LIU
;
Wei MA
;
Jianjiang ZHANG
Author Information
1. 郑州大学第一附属医院儿童重症监护室，郑州 450000
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(19):1496-1498
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To report 1 case of mushroom poisoning complicated with multiple organ dysfunction syndrome treated by liver transplantation, so as to explore surgical effectiveness and prognosis of liver transplantation on children mushroom poisoning.Methods:Retrospectively analyzed a child with mushroom poisoning who was admitted to the First Affiliated Hospital of Zhengzhou University in June 2017.Conventional treatment was not ideal, the child was conducted orthotopic liver transplantation.The effectiveness was evaluated and the feasibility of liver transplantation in treating children mushroom poisoning with literatures was reviewed.Results:A male 2-year old child obtained, preo-perative Child-pugh class for C. This child recovered well postoperatively, the jaundice disappeared, and liver enzyme and blood coagulation function improved significantly within 1 week after liver transplantation.However, the head magnetic resonance imaging presented brain atrophy and ventricular expansion, with intelligence and athletic ability being significantly behind his peers through postoperative regular follow-up for 2 years.Conclusion:Fulminant hepatic failure that was caused by mushroom poisoning is an indication for liver transplantation, and orthotopic liver transplantation is an effective method for the treatment of mushroom poisoning, which can effectively improve liver function, metabolic disorders and blood coagulation function for children with mushroom poisoning, but nervous system damage that was caused by mushroom poisoning is irreversible.Although liver transplantation technology successfully cured liver failure, it still left severe neurological sequelae.
