Study progress of respiratory complications of primary immunodeficiencies in children
10.3760/cma.j.cn101070-20190527-00455
- VernacularTitle:儿童原发性免疫缺陷病呼吸系统并发症研究进展
- Author:
Huifeng FAN
1
;
Chen CHEN
;
Gen LU
Author Information
1. 广州医科大学附属广州市妇女儿童医疗中心呼吸科 510120
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(16):1274-1277
- CountryChina
- Language:Chinese
-
Abstract:
Primary immunodeficiencies (PIDs) are caused by one or more defects of the immune system.Children with PIDs are more likely to experience recurrent and/or severe infections and tend to develop a wide range of complications.Respiratory diseases are the main and initial manifestation in most cases.Pulmonary complications have significant morbidity and mortality in children with PIDs.The spectrum of pathogens usually varies among different types of PID.Early diagnosis and appropriate therapy can prevent or at least slow down the development and course of respiratory complications of PIDs.In this study, the main respiratory manifestations of common PIDs in children are reviewed.