Application of metagenomics detection of pathogenic microorganisms in neonatal infectious diseases
10.3760/cma.j.cn101070-20200224-00237
- VernacularTitle:病原微生物宏基因组检测在新生儿感染性疾病中的应用
- Author:
Pu XU
1
;
Laishuan WANG
Author Information
1. 复旦大学附属儿科医院新生儿科，上海 201102
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(11):820-823
- CountryChina
- Language:Chinese
-
Abstract:
The clinical manifestations of neonatal infectious diseases are diverse, lacking specificity, and it may involve multiple organs or systems.At present, there are many clinical indicators of neonatal infectious diseases, each of which has its advantages and disadvantages, and it is difficult to meet the requirements of current diagnosis and treatment.Clinical metagenomic next-generation sequencing (mNGS) can accurately and efficiently analyze the genetic material information of all pathogenic microorganisms, so as to directly detect pathogenic microorganisms for diagnosis and treatment, which has important reference value for the diagnosis of neonatal infectious diseases.Now, the recent advances in metagenomics detection of pathogenic microorganisms and its application in neonatal infectious diseases were reviewed.
