Clinical features of 9 children with osteomyelitis caused by Streptococcus pneumonia
10.3760/cma.j.cn101070-20191030-01066
- VernacularTitle:儿童急性肺炎链球菌骨髓炎9例临床特征分析
- Author:
Xue NING
1
;
Jikui DENG
;
Shihua LIU
;
Biquan CHEN
;
Huiling DENG
;
Yanhong ZHANG
;
Gang LIU
Author Information
1. 国家儿童医学中心，首都医科大学附属北京儿童医院感染内科，儿科重大疾病研究教育部重点实验室，北京 100045
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(8):605-608
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical features, diagnosis, treatment and prognosis of children with osteomyelitis caused by Streptococcus pneumonia. Methods:The demographic characteristics, diagnosis, clinical manifestations, imaging features, treatment and short-term prognosis of Streptococcus pneumonia osteomyelitis cases in 18 children′s hospitals from January 2012 to December 2017 were retrospectively collected and analyzed. Results:A total of 9 cases were enrolled, with a median age of 1 year and 3 months.Four children had underlying diseases.The main manifestations were local swelling, pain, limited mobility (9 cases) and fever (8 cases). Sites of infection included humerus (4 cases), femur (3 cases) and tibiofibula (2 cases), and 8 cases were complicated with septic arthritis; The laboratory tests showed increased white blood cells (8 cases, median 22.02×10 9/L), C-reactive protein (7 cases, median 55.44 mg/L) and erythrocyte sedimentation rate (6 cases, median 70 mm/1 h) of those patients.Five patients received monotherapy in the initial treatment regimen with cephalosporins. Then the therapeutic schedules were adjusted according to the culture and antibiotic sensitivity. All patients were treated with puncture, incision drainage or fenestrating decompression.Eight patients were cured and discharged finally. Conclusions:Streptococcus pneumonia osteomyelitis is more common in younger children and may have no risk factors.The common infection site is long bone metaphysis, and those patients are easily complicated with septic arthritis.Antibiotic combined with surgical treatment are crucial to a good outcome.
