Progress in sepsis-associated encephalopathy therapy
10.3760/cma.j.cn101070-20200309-00356
- VernacularTitle:脓毒症相关性脑病治疗进展
- Author:
Yibing CHENG
1
;
Meng WANG
Author Information
1. 郑州大学附属儿童医院，河南省儿童医院急诊科 450000
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(6):415-418
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis-associated encephalopathy (SAE) is a common complication of sepsis.Not only the cognitive impairment which may develop in the future can reduce the quality of life, but also there is a high mortality in patients with this complication.There is no clear pathogenesis characterized and no specific therapy developed up to date.The synthetic treatment for sepsis is the most commonly used therapy.However, the treatment for encephalopathy is still under research.Therapy that can reduce inflammation caused by SAE, protect the blood-brain barrier, inhibit neurotransmitter abnormality, and restrain other key pathophysiology injuries should be developed in the future to prevent the permanent brain functional damage caused by SAE in patients.
