Pathogenicity of H5N8 virus in chickens from Korea in 2014.
10.4142/jvs.2015.16.2.237
- Author:
Byung Min SONG
1
;
Hyun Mi KANG
;
Eun Kyoung LEE
;
Jipseol JEONG
;
Yeojin KANG
;
Hee Soo LEE
;
Youn Jeong LEE
Author Information
1. Division of Avian Diseases, Animal and Plant Quarantine Agency, Anyang 430-757, Korea. leeyj700@korea.kr
- Publication Type:Brief Communication ; Research Support, Non-U.S. Gov't
- Keywords:
chicken;
H5N8;
highly pathogenic avian influenza;
pathogenicity
- MeSH:
Animals;
Chickens;
Disease Outbreaks/veterinary;
Influenza A virus/*pathogenicity/*physiology;
Influenza in Birds/*mortality/transmission/virology;
Poultry Diseases/*mortality/transmission/virology;
Republic of Korea/epidemiology;
Virulence
- From:Journal of Veterinary Science
2015;16(2):237-240
- CountryRepublic of Korea
- Language:English
-
Abstract:
In 2014, two genetically distinct H5N8 highly pathogenic avian influenza (HPAI) viruses were isolated from poultry and wild birds in Korea. The intravenous pathogenicity indices for the two representative viruses were both 3.0. Mortality of chickens intranasally inoculated with the two H5N8 viruses was 100% with a mean death times of 2.5 and 4.5 days. Mortality rates of the contact groups for the two H5N8 viruses were 33.3% and 66.6%. Our study showed that transmissibility of the novel H5N8 viruses was different from that of previously identified H5N1 HPAI viruses, possibly due to genetic changes.
