Intrapancreatic ectopic splenic tissue found in a cloned miniature pig.
10.4142/jvs.2015.16.2.241
- Author:
Ok Jae KOO
1
;
Seung Kwon HA
;
Sol Ji PARK
;
Hee Jung PARK
;
Su Jin KIM
;
Daekee KWON
;
Jung Taek KANG
;
Joon Ho MOON
;
Eun Jung PARK
;
Goo JANG
;
Byeong Chun LEE
Author Information
1. Laboratory Animal Research Center, Samsung Biomedical Research Institute, Suwon 440-746, Korea.
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
cloned pig;
intrapancreatic ectopic splenic tissue;
somatic cell nuclear transfer
- MeSH:
Animals;
Animals, Genetically Modified;
Choristoma/pathology/*veterinary;
Cloning, Organism;
Nuclear Transfer Techniques/*veterinary;
*Pancreas;
Splenic Diseases/pathology/*veterinary;
Swine;
Swine Diseases/*pathology;
Swine, Miniature
- From:Journal of Veterinary Science
2015;16(2):241-244
- CountryRepublic of Korea
- Language:English
-
Abstract:
Somatic cell nuclear transfer (SCNT) is a cost-effective technique for producing transgenic pigs. However, abnormalities in the cloned pigs might prevent use these animals for clinical applications or disease modeling. In the present study, we generated several cloned pigs. One of the pigs was found to have intrapancreatic ectopic splenic tissue during histopathology analysis although this animal was grossly normal and genetically identical to the other cloned pigs. Ectopic splenic tissue in the pancreas is very rare, especially in animals. To the best of our knowledge, this is the first such report for cloned pigs.
