An Adult Case of Fisher Syndrome Subsequent to Mycoplasma pneumoniae Infection.
10.3346/jkms.2013.28.1.152
- Author:
So Yeon LEE
1
;
Yong Hoon LEE
;
Bo Young CHUN
;
Shin Yup LEE
;
Seung Ick CHA
;
Chang Ho KIM
;
Jae Yong PARK
;
Jaehee LEE
Author Information
1. Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea. jaelee@knu.ac.kr
- Publication Type:Case Reports
- Keywords:
Mycoplasma pneumoniae;
Fisher Syndrome;
Anti-GQ1b Antibody
- MeSH:
Adult;
Anti-Bacterial Agents/therapeutic use;
Antibodies/blood;
Diplopia/etiology;
Erythrocyte Count;
Gangliosides/immunology;
Humans;
Lung/radiography;
Male;
Miller Fisher Syndrome/*diagnosis/etiology;
Pneumonia, Mycoplasma/complications/*diagnosis/drug therapy;
Tomography, X-Ray Computed
- From:Journal of Korean Medical Science
2013;28(1):152-155
- CountryRepublic of Korea
- Language:English
-
Abstract:
Reported herein is an adult case of Fisher syndrome (FS) that occurred as a complication during the course of community-acquired pneumonia caused by Mycoplasma pneumoniae. A 38-yr-old man who had been treated with antibiotics for serologically proven M. pneumoniae pneumonia presented with a sudden onset of diplopia, ataxic gait, and areflexia. A thorough evaluation including brain imaging, cerebrospinal fluid examination, a nerve conduction study, and detection of serum anti-ganglioside GQ1b antibody titers led to the diagnosis of FS. Antibiotic treatment of the underlying M. pneumoniae pneumonia was maintained without additional immunomodulatory agents. A complete and spontaneous resolution of neurologic abnormalities was observed within 1 month, accompanied by resolution of lung lesions.
